Lecture by Prof. Ilona Kryczek from the University of Michigan

We warmly invite you to a lecture by Prof. Ilona Kryczek from the Department of Surgery at the University of Michigan. The lecture will take place on Monday 23 March 2023 at 2.00 pm in the IIET PAS Lecture Hall.

Title: ‘A breakthrough in cancer immunology: checkpoints, cell death mechanisms and metabolic pathways’.

After the lecture, we invite you to join us for further conversation and an informal discussion in Room 138.

Professor Ilona Kryczek has been affiliated with the Department of Surgery at the University of Michigan for over 20 years, where she has built a world-class research career in the field of cancer immunology and T-cell biology. She is an internationally recognised expert in the field of tumour immunosuppression, and her scientific achievements have had a lasting impact on the development of modern immunotherapy strategies.

Prof. Kryczek leads several research programmes focusing on the mechanisms of adaptation, function and regulation of T cells within the tumour microenvironment. She heads an interdisciplinary team comprising postdoctoral researchers, PhD students, research staff and undergraduates, developing innovative research projects and providing extensive mentoring support to early-career researchers. Her experience includes managing large-scale projects, leading research teams and developing international collaboration networks, which makes her ideally suited to lead a centre of excellence within the MAB project.

Professor Kryczek’s academic output includes over 150 publications in prestigious scientific journals and more than 34,000 citations. Her research has significantly advanced our understanding of the complex interactions between T cells and cancer cells. Her particular contribution concerns the role of metabolites and metabolic regulators in modulating the function of immune system cells, which opens up new prospects for personalised cancer therapy. Research into TCR receptor signalling and the influence of the cytokine environment has contributed to the development of innovative therapeutic approaches in immuno-oncology. The latest discoveries by Prof. Kryczek’s team concerning the metabolic susceptibility of tumours and its modulation by T lymphocytes point to new possibilities for enhancing the efficacy of cancer treatment.