Mateusz Noszka, Jakub Muraszko and Anna Pawlik from the Laboratory of Molecular Biology of Microorganisms published their work in Nature Communications (200 MEiN points, IF 16.6). The study showed that over 30% of Helicobacter pylori genes are under the transcriptional control of the HP1021 protein, including such important cellular processes as response to oxidative stress, DNA uptake, necessary for the virulence of this bacterium, and carbohydrate metabolism, important for the energy state of the cell.
The work was done in multi-center cooperation, financed by the National Science Center (OPUS 17, 2019/33/B/NZ6/01648), the Horizon 2020 Framework Program of the European Union (EPIC-XS, no. 823839) and the Institute of Immunology and Experimental Therapy of the Polish Academy of Sciences in Wrocław.